Actizen Tablet

10 mg
Ambee Pharmaceuticals Ltd.

Pack Size & Price:

100's pack : ৳ 203.00 (Unit Price : ৳ 2.03)

Indications

Cetirizine is indicated for the treatment of seasonal allergic rhinitis and conjunctivitis, perennial allergic rhinitis, pruritus and urticaria. It is also used in allergen induced asthma.

Therapeutic Class

Sedating Anti-histamine

Pharmacology

Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and respiratory tract.

Dosage & Administration

Tablet:
  • Adults and children over 6 years: 1 tablet (10 mg) once daily or ½ tablet twice daily. 
  • Children 2-6 years: ½ tablet once daily.
Syrup:
  • Adults and children over 6 years: 2 teaspoonful (10 mg) once daily or 1 teaspoon (5 mg) twice daily. 
  • Children 2-6 years: 1 teaspoonful once daily or ½ teaspoon twice daily.

Interaction

No clinically significant drug interactions have been found with theophylline, azithromycin, pseudoephedrine, ketoconazole or erythromycin and with some other drugs.

Contraindications

Cetirizine Dihydrochloride is contraindicated in those patients with a known hypersensitivity to it or any of its ingredients or hydroxyzine.

Side Effects

Cetirizine dihydrochloride is well tolerated. Lower incidence of sedation, headache, dry mouth, and gastrointestinal disturbances may occur. It does not produce anticholinergic effects.

Pregnancy & Lactation

Pregnancy category B. There are no adequate and well controlled studies in pregnant women. Cetirizine should be used during pregnancy only if clearly needed. Cetirizine has been reported to be excreted in human breast milk. As large amount of drugs are excreted in human milk, use of Cetirizine in nursing mother is not recommended.

Precautions

Caution should be exercised when driving a car or operating a heavy machinery. Concurrent use of cetirizine with alcohol or other CNS depressants should be avoided because additional reduction in alertness and CNS performance may occur.

Overdose Effects

Symptoms: Confusion, dizziness, fatigue, headache, malaise, restlessness, sedation, somnolence, diarrhoea, mydriasis, pruritus, stupor, tachycardia, tremor, and urinary retention.

Management: Symptomatic and supportive treatment. Gastric lavage may be done shortly following ingestion.

Storage Conditions

Store between 20-25°C. Syrup: Store between 2-8°C.