1stCef Capsule

500 mg
Medimet Pharmaceuticals Ltd.

Pack Size & Price:

Unit Price : ৳ 12.00

Indications

Cefadroxil is indicated in skin and skin structure infections, Streptococcal pharyngitis, Tonsillitis, Urinary tract infections

Therapeutic Class

First generation Cephalosporins

Pharmacology

Cefadroxil inhibits bacterial cell wall synthesis by binding to 1 or more of the penicillin-binding proteins (PBPs) which in turn inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

Dosage & Administration

Adult: 1-2 g daily as a single or in 2 divided doses.
Child: ≥6 yr <40 kg: 30-50 mg/kg daily as a single or in 2 divided doses, up to 100 mg/kg daily.

Interaction

Prothrombin time will be prolonged; bleeding may occur when taken with anticoagulants. Decreased elimination with Probenecid is also reported.

Contraindications

Cefadroxil is contraindicated in patients with a history of hypersensitivity to any of the ingredients.

Side Effects

Generally well tolerated. The most commonly reported side effects are gastrointestinal disturbances and hypersensitivity, nausea, vomiting, diarrhoea, dyspepsia, abdominal discomfort, fever, dizziness, headache, arthralgia may also occur.

Pregnancy & Lactation

Pregnancy category B. But it should be used only if clearly needed. Caution should be exercised when Cefadroxil is administered to a nursing mother

Precautions

History of hypersensitivity to penicillins or any other β-lactam drugs. History of GI disease (particularly colitis), severe allergies or asthma. Renal impairment. Pregnancy and lactation.

Overdose Effects

Symptoms: Nausea, hallucinations, hyperreflexia, extrapyramidal symptoms, clouded consciousness, or even coma and renal function impairment.

Management: Induce vomiting at once or gastric lavage; haemodialysis if needed. Monitor and if necessary, correct water and electrolyte balance.

Storage Conditions

Store between 20-25°C. Reconstituted powder for suspension: Store between 2-8°C.