60 ml bottle:
৳ 175.00
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Indications
Adinir is indicated for the treatment of Community Acquired Pneumonia, Acute Exacerbation of Chronic Bronchitis, Acute Maxillary Sinusitis, Pharyngitis, Tonsillitis, Uncomplicated Skin and Skin Structure, Infections
Pharmacology
Cefdinir binds to 1 or more of the penicillin-binding proteins (PBPs) which inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Dosage & Administration
Adult: 600 mg daily as a single or in 2 divided doses for 5-10 days.
Child: ≥6 months: 14 mg/kg daily as a single or in 2 divided doses. Max: 600 mg daily.
Child: ≥6 months: 14 mg/kg daily as a single or in 2 divided doses. Max: 600 mg daily.
Interaction
Antacids: Adinir should be taken at least 2 hours interval of antacid administration.
Iron supplement: Adinir should be taken at least 2 hours interval of iron supplement administration.
Probencid: It inhibits the renal excretion of Adinir.
Iron supplement: Adinir should be taken at least 2 hours interval of iron supplement administration.
Probencid: It inhibits the renal excretion of Adinir.
Contraindications
Cefdinir is contraindicated in patients with known allergy to the cephalosporin class of antibiotics.
Side Effects
Common side effects are Diarrhea, Vaginal moniliasis, Nausea & Vomiting, Headache, Rash etc.
Pregnancy & Lactation
Pregnancy Category B. There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. Following administration of single 600 mg doses, Cefdinir was not detected in human breast milk.
Precautions & Warnings
Adinir, as with other broad-spectrum antibiotics, should be prescribed with caution in individuals with a history of colitis. In patients with transient or persistent renal insufficiency (creatinine clearance <30 ml/min), the total daily dose of Adinir should be reduced.
Overdose Effects
Symptoms: Nausea, vomiting, epigastric distress, diarrhoea, convulsions.
Management: Haemodialysis may be useful in the event of a serious toxic reaction particularly if renal function is compromised.
Management: Haemodialysis may be useful in the event of a serious toxic reaction particularly if renal function is compromised.
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Store between 20-25° C.