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Indications

Aztrum-I is indicated for Age-related Eye Disease. This is an advanced new antioxidant supplement formulated to provide nutritional support for the eye. The formulation contains essential antioxidant vitamins, minerals, and Lutein.

Composition

Each capsule contains -
  • Vitamin C 60 mg
  • Vitamin E 30 mg
  • Lutein Ph.grade 6 mg
  • Copper (as Cupric oxide) Ph.grade 2 mg
  • Zinc (as Zinc oxide) BP 15 mg

Pharmacology

Vitamin C is highly concentrated in the lens compared to blood. A long term Vitamin C supplement use (10+ years) has been associated with reduced risk of cataract. Vitamin C has an important role in harmful free radicals scavenging activity.

In study, it is found that high serum Vitamin E concentrations have been associated with reduced risk of cataract (exact mechanism of action is not still established). As an antioxidant vitamin, it also plays an important role in harmful free radicals scavenging activity.

Lutein is a carotenoid, specially concentrated in the macula. Clinical and animaldata indicates that this caretenoid could protect the macula from oxidative or light damage.

Although exact mechanism of action is not clear but onelarge study has found that high levels of dietary Lutein is associated with relatively lower risk of AMD (Age-Related Macular Degeneration). Zinc is an essential trace element involved in many enzymes system.

Symptoms of less severe deficiency include distorted or absent perception of taste, smell and poor wound healing. Severe deficiency causes skin lesion, alopecia, diarrhea, increased susceptibility to infection and failure to thrive in children.

Copper plays important role in growth, skeletal integrity, and development of nervous system. As a part of various enzymes, it takes part in numerous metabolic conversions.

Dosage & Administration

One capsule, one or two times daily or as directed by the physician

Interaction

No drug interaction has been reported.

Contraindications

It is contraindicated in persons with a history of hypersensitivity to any of its ingredients.

Side Effects

Large doses of Vitamin C are reported to cause diarrhoea and other gastrointestinal disturbances. Large doses of Vitamin E may cause diarrhoea, abdominal pain, and other gastrointestinal disturbances; fatigue and weakness have also been reported. Side effects of Zinc salt are abdominal pain and dyspepsia.

Pregnancy & Lactation

Recommended in Pregnancy & Lactation.

Precautions & Warnings

Vitamin C should be given with care to patients with hyperoxaluria. In patients taking oral anticoagulants or oestrogen, Vitamin E should be given carefully because it has been found to antagonise the effects of vitamin K leading to an increase in blood clotting time in these patient

Therapeutic Class

Anti-oxidant Multivitamin Multimineral preparations, Antioxidant vitamins & minerals for eye

Storage Conditions

Store in a dry place below 25° C. Protect from light.
Pack Image of Aztrum-I 60 mg Capsule Pack Image: Aztrum-I 60 mg Capsule