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Indications

Kontab is indicated for inflammatory pains, soft tissue inflammation, edema associated with trauma and surgery such as in gynaecological conditions, breast engorgement, fractures, sprains, injuries, hemorrhoid, anal prolapse

Pharmacology

Trypsin is an enzyme. An enzyme is a protein that speeds up a certain biochemical reaction. Trypsin is found in the small intestine. It can also be made from fungus, plants, and bacteria. But it is usually made for commercial purposes from the pancreas of livestock. Trypsin is given to people who lack enzymes needed for digestion. It is also given in combination with bromelain and rutin for treatment of osteoarthritis.

Bromelain is a protein extract derived from the stems of pineapples, although it exists in all parts of the fresh plant and fruit. The extract has a history of folk medicine use. As a culinary ingredient, it may be used as a meat tenderizer. The term "bromelain" may refer to either of two protease enzymes extracted from the plants of the family Bromeliaceae, or it may refer to a combination of those enzymes along with other compounds produced in an extract.

Dosage & Administration

Initially 2 tabs 3 times daily. Maintenance 1 tab 3 times daily preferably before meals

Interaction

There are no known drug interactions and none well documented.

Contraindications

Hypersensitivity.

Side Effects

Trypsin seems to be safe when used by healthcare professionals for wound cleaning and healing. It can cause side effects such as pain and burning. Not enough is known about the safety of trypsin for its other uses.

Pregnancy & Lactation

Pregnancy Category-Not Classified. FDA has not yet classified the drug into a specified pregnancy category.

Precautions & Warnings

Allergies: If you are allergic to pineapple, latex, wheat, celery, papain, carrot, fennel, cypress pollen, or grass pollen, you might have an allergic reaction to bromelain.

Surgery: Bromelain might increase the risk of bleeding during and after surgery. Stop using bromelain at least 2 weeks before a scheduled surgery.

Therapeutic Class

Enzymes