Injection

Gentacin Injection

Veterinary
50 mg/ml
10 ml vial: ৳ 30.00
50 ml vial: ৳ 120.00
100 ml vial: ৳ 235.00
Also available as:

Indications

Broad spectrum antibiotic widely used for the treatment of urinary and respiratory tract infections. For the treatment of severe infections caused by susceptible gram positive and gram negative bacteria including species of pseudomonas, proteus, many coliform bacilli and mycoplasma as well. Effective in enteric disease of neonates like scour and salmonellosis.

Benefits of Gentacin Sulphate Injection:
  • Active against most gram negative and gram positive bacteria
  • Significantly reduces early chick and pullet mortality
  • Bactericidal at low dose
  • Rapid tissue distribution, bioavailability from extravascular injection is greater than 90%
  • Prolonged activity in major organs
  • Drug of choice in cases of resistance to other antibiotics as oxytetracycline, chloramphenicol and sulphonamides

Pharmacology

Gentamicin is a broad spectrum aminoglycoside antibiotic which is highly effective against many strains of Gram Negative and Gram Positive micro-organisms such as E.coli, Salmonella, Pasteurella, Staphylococcus, Streptococcus, Listeria, Pseudomonus, etc. The oral Gentamicin is slowly and poorly absorbed from the gastrointestinal tract hence it concentrates in the intestine that shows its antibacterial action locally and leading to a high efficacy against the bacterial gastro enteric infections.

Dosage & Administration

For intramuscular/intravenous injection only
  • Cattle/Buffalo/Horse: 1.0 ml/25 kg body weight.
  • Goat/Sheep/Dog/Cat/Other small animals: 0.4-1.0 ml/10 kg body weight.
  • Administer by deep intramuscular or slow intravenous injection twice on the first day of treatment at 12 hours interval and repeat from second day once daily for 3-5 days.
For intramuscular/subcutaneous injection only
  • Poultry: 0.05-0.1 ml/ kg body weight.
  • Administer by intramuscular or subcutaneous injection twice on the first day of treatment at 12 hours interval and repeat from 2 nd day once daily for 3-5 days. Or, as directed by the Registered Veterinary Physician.
Oral Powder: Treatment:
  • Poultry: 1 g per 2 liters of drinking water for 3-5 days.
  • Cattle, Sheep & Goat (and off-spring): 3 g per 20 kg bodyweight twice daily for 3-5 days (30 mg/ kg Body Weight). Or advised by the registered veterinarian.

Interaction

With medicine: Potential drug interaction may occur with other aminoglycosides and bacteriostatic antibiotics.

With feed & others: Not known.

Contraindications

Gentamicin Injection is contraindicated to patients hypersensitive to Gentamicin. It is contraindicated in pregnancy and myasthenia gravis.

Side Effects

Common side effects: Nausea, vomiting, stomach upset, loss of appetite, and injection site reactions (pain, irritation, and redness) may be seen.

Rare side effects: Hypocalcemia, neuromuscular paralysis, nephrotoxicity and ototoxicity have been reported with high and prolonged medication.

Pregnancy & Lactation

Should not be used in pregnant or lactating animals. However, risk & necessity should be considered during administration of medicine in pregnant & lactating animals.

Precautions & Warnings

Antibiogram is recommended before administration. In case of urinary tract infection alkaline feed is recommended.

Withdrawal period: Meat: 7 days & Milk: 2 days.

Overdose Effects

Early signs of toxicity include loss of hearing and balance or vomiting. Moreover, increase or decrease in water intake, loss of appetite, depression, coma and death may be reported.

Storage Conditions

Protect from light, store in a cool and dry place. Keep out of reach of children.