Bolus Tablet

S-Zol Bolus Tablet

Veterinary
600 mg
Unit Price: ৳ 7.50 (4 x 5: ৳ 150.00)
Strip Price: ৳ 37.50
Also available as:

Indications

It is used as anthelmintic against most nematodes and cestodes. S-Zol is effective against these gastrointestinal parasites: Bunostomum, Chabertia, Cooperia, Haemonchus, Nematodirus, Ostertagia, Strongyloides, Dictyocaulus viviparus, Moniezia expansa, Liver flukes and Paramphistomes. It is also effective against different types of worms, lung flukes and lung nematodes.

Benefits:
  • Ideal for multiple helminth viz. round worms, tape worms, lung worms and flukes.
  • Proven broad spectrum activity against mature and immature stages of worms.
  • Wide safety margin, no side effects.
  • In pregnant animals can be used after 1st month of pregnancy.

Pharmacology

Benzimidazoles bind to b-tubulin, which in turn prevents its dimerization with a-tubulin and the polymerization of tubulin oligomers into microtubules. Microtubules are essential structural units of many organelles and are necessary for numerous processes, including protein assembly, and energy metabolism. Mammals also rely on tubulin for cellular metabolism but BZDs have a higher affinity for nematode tubulin at normal body temperature range of mammals.

Dosage & Administration

Cattle & Buffaloes:
  • Roundworms, Tapeworms, Lungworms: 7.5 mg/kg
  • Liver Flukes: 10 mg/kg
Sheep & Goats:
  • Roundworms, Tapeworms, Lungworms: 5 mg/kg
  • Liver Flukes: 7.5 mg/kg
Horses:
  • Roundworms, Pinworms: 7.5 mg/kg
  • Lungworms: 25 (b.i.d.) for 5 days
Dogs & Cats:
  • Roundworms, Whipworms, Hookworms, Tapeworms, Lungworms, Bladderworms, Liver flukes: 15 mg/kg

Side Effects

In several cases nausea, vomiting may occur.

Precautions & Warnings

Safety index: Wide safety margin than any other group due to greater selective affinity for parasitic b-tubulin than for animal tissues.

Withdrawal period: Meat: 8-14 days, Milk: 3-5 days

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.