Indications

Curex lotion is indicated for the treatment of itching and skin irritation caused by, for example sunburn, dry eczema, itchy dermatitis, allergic rashes, hives, nettle rash, chickenpox, insect bites and stings, heat rashes and personal itching. Curex lotion is also indicated for the treatment of pruritus after scabies.

Pharmacology

Crotamiton is an antiparasitic that is toxic to the scabies mite. Crotamiton also relieves itching by producing what is called a counter-irritation. As crotamiton evaporates from the skin, it produces a cooling effect. This cooling effect helps to divert your body's attention away from the itching.

Dosage & Administration

Pruritus:
  • Adults (including the elderly) and children: Apply to the affected area 2-3 times daily. Crotamiton lotion will provide relief from irritation for 6-10 hours after each application. Crotamiton lotion can be used in children. There are no special dosage recommendations in the elderly.
Pruritus after scabies:
  • Adults (including the elderly): After the patient has taken a warm bath, the skin should be well dried and Crotamiton lotion rubbed into the entire body surface (excluding the face and scalp) until no traces of the preparation remain visible on the surface. The application should be repeated once daily, preferably in the evening, for a total of 3-5 days. Depending on the response, special attention should be paid to sites that are particularly susceptibly to infestation by the mites (eg interdigital spaces, wrists, axillae and genitalia). Areas where there is pus formation should be covered with a dressing impregnated with Crotamiton lotion. While the treatment is in progress the patient may take a bath shortly before the next application. After completion of the treatment, a cleansing bath should be taken followed by a change of bed linen and underclothing.
  • Children: Application as described for adults but in children under 3 years of age Crotamiton lotion should not be applied more than once a day

Contraindications

Acute exudative dermatoses. Crotamiton 10% lotion is contra-indicated in patients with known hypersensitivity to crotamiton. Crotamiton 10% lotion should not be used in or around the eyes since contact with the eyelids may give rise to conjunctival inflammation.

Side Effects

Occasionally irritation of the skin or contact allergy may occur. In such cases the preparation should be discontinued.

Pregnancy & Lactation

There is no experience to judge the safety of Cronix lotion in pregnancy, therefore Cronix lotion is not recommended during pregnancy, especially in the first three months. It is not known whether the active substance passes into breast milk. Nursing mothers should avoid applying Cronix lotion in the area of the nipples.

Precautions & Warnings

Curex lotion can be used for children; consult your doctor before use on children under 3 years of age. For external use only. Do not use in or around the eyes, on broken skin, for weeping skin conditions or if you are sensitive to any of the ingredients. Keep all medicines out of the reach of children. Consult your doctor before using Curex 10% lotion if you are pregnant or breast feeding, or suffering from genital itching. If symptoms persist consult your doctor.

Overdose Effects

Curex lotion is for application to the skin only. Following accidental ingestion, nausea, vomiting and irritation of the buccal, oesophageal and gastric mucosa have been reported. If accidental ingestion of large quantities occurs, there is no specific antidote and general measures to eliminate the drug and reduce its absorption should be undertaken. Symptomatic treatment should be administered as appropriate. A risk of methaemoglobinaemia exists, which may be treated with methylene blue.

Therapeutic Class

Local Antipruritic, Parasiticidal preparations

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Pack Image of Curex 10% Cream Pack Image: Curex 10% Cream