Aluminium Oxide + Magnesium Trisilicate
Indications
Aluminium Oxide & Magnesium Trisilicate is indicated in Heartburn, Indigestion, Gastric Hyperacidity, Peptic ulcer disease, Gastroesophageal reflux disorder (GERD)
Pharmacology
Aluminum hydroxide neutralizes stomach hydrocloride to form AICI3 salt plus water; increases gastric pH.
Magnesium Trisilicate neutralizes gastric acidity by increasing gastric pH
Magnesium Trisilicate neutralizes gastric acidity by increasing gastric pH
Dosage & Administration
Take 2-4 teaspoonful after meals and at bedtime as needed (up to 4 times a day)
Interaction
Aluminium Hydroxide: Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine.
Magnesium Trisilicate: None well documented.
Magnesium Trisilicate: None well documented.
Contraindications
Hypophosphataemia
Side Effects
Diarrhoea, constipation, nausea, vomiting.
Pregnancy & Lactation
Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category.
Precautions & Warnings
Renal dysfunction, low phosphate diet, prolonged use.
Therapeutic Class
Antacid with laxative action, Antacids