Vitamin C + Vitamin D3 + Folic acid
Indications
Calcium and Vitamin-D is used for the treatment of osteoporosis, osteomalacia, rickets, tetany, and parathyroid disease. Also used in raised calcium requirement for children and adolescents at times of rapid growth, inadequate intake of calcium in the diet due to malnutrition, prevention and treatment of osteoporosis, disorders of osteogenesis and tooth formation (in addition to specific treatment), latent tetany and during pregnancy and lactation. It is also used as routine supplement and phosphate binder in chronic renal failure.
Pharmacology
Ascorbic acid (vitamin C) & Folic acid (also known as Vitamin B9) are water-soluble vitamins. Vitamin D is fat-soluble. Ascorbic acid helps integration & cohesiveness of cells by synthesizing collagen which is also known as biological glue. It is also a powerful antioxidant in the aqueous media. Vitamin D is also known as antirachitic and sun-shine vitamin which displays its roles like a hormone (pro-hormone). Vitamin D spares calcium in the body by reducing excretion and enhancing calcium absorption. Folic acid is crucial for proper brain function and plays an important role in mental and emotional health. It aids in the production of DNA and RNA, the body's genetic material, and is especially important during periods of high growth, such as infancy, adolescence and pregnancy. It controls blood levels of the amino acid Homocysteine. Elevated levels of this substance appear to be linked to certain chronic conditions such as heart disease. Indications: Deficiency states of Vitamin C, Vitamin D and Folic acid associated with cardiovascular diseases, Deficiency states of Vitamin-C (Scurvy, generalized weakness, gum bleeding, after acute infections, alcoholism and postoperatively), Wound healing, Prevention of cold, flue and influenza, Megaloblastic anemia and anemia of nutritional origin, Deficiency states of Vitamin-D (Intestinal malabsorption, chronic liver disease, osteomalacia, osteopenia, rickets, hypocalcemia, institutionalized patients, persons who use sunscreen, black people, person who covers most of the body surface due to cultural and religious purpose). Familial hypophosphatemia, Hypoparathyroidism, As adjuvant with calcium supplement, Prevention of osteoporosis and fracture alone or in combination with calcium supplement, Conditions where demand for Vitamin-C, Vitamin-D and Folic acid increases (pregnancy, lactation, smoking and old age, person living in polluted environment).
Dosage & Administration
One tablet twice daily with food or as directed by the physician.
Interaction
Concurrent administration of Thiazide diuretics may increase the risk of hypercalcemia. Calcium salts reduce the absorption of a number of other drugs such as Biphosphonates, Fluoride, some Fluoroquinolones and Tetracyclines.
Contraindications
- Hypercalcemia and hyperparathyroidism
- Hypercalciuria and nephrolithiasis
- Hypersensitivity to the component of this preparation
- Severe renal insufficiency
- Concomitant digoxin therapy(requires careful monitoring of serum calcium level)
Side Effects
Vitamin C, Vitamin D3 & Folic acid combination is well tolerated. Mild gastrointestinal disturbances may occur.
Pregnancy & Lactation
Pregnancy: There is no contraindication to the use of this preparation in pregnancy.
Lactation: There is no contraindication to the use of this preparation in Lactation. Contraindications: This combination is contraindicated in hypercalcemia, hyperparathyroidism, renal calculi, nephrolithiasis, Zoolinger-Ellison syndrome, concomitant Digoxin therapy (requires careful monitoring of serum calcium level).
Lactation: There is no contraindication to the use of this preparation in Lactation. Contraindications: This combination is contraindicated in hypercalcemia, hyperparathyroidism, renal calculi, nephrolithiasis, Zoolinger-Ellison syndrome, concomitant Digoxin therapy (requires careful monitoring of serum calcium level).
Precautions & Warnings
Caution should be taken in patients with Renal impairment, Sarcoidosis, Hypercalcemia and Hypercalciuria, Cardiac disease.
Overdose Effects
Over dosage: If over dosage occurs, therapy should be immediately stopped.
Therapeutic Class
Specific combined vitamin preparations
