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1000 ml bag: ৳ 70.80

Composition

Each 100 ml of solution contains-
  • Calcium Chloride 22 mg
  • Dextrose Anhydrous 1.5 gm
  • Magnessium Chloride 15.2 mg
  • Sodium Acetate 476 mg
  • Sodium Chloride 556 mg 

Indications

This is indicated for Peritoneal Dialysis.

Pharmacology

Calcium chloride is used to prevent or treat negative calcium balance. It also regulates action potential excitation threshold to facilitate nerve and muscle performance.

Potassium chloride is a major cation of the intracellular fluid. It plays an active role in the conduction of nerve impulses in the heart, brain and skeletal muscle; contraction of cardiac skeletal and smooth muscles; maintenance of normal renal function, acid-base balance, carbohydrate metabolism and gastric secretion.

Sodium chloride is the major extracellular cation. It is important in electrolyte and fluid balance, osmotic pressure control and water distribution as it restores sodium ions. It is used as a source of electrolytes and water for hydration, treatment of metabolic acidosis, priming solution in haemodialysis and treatment of hyperosmolar diabetes. It is also used as diluents for infusion of compatible drug additives.

Sodium lactate is a sterile, nonpyrogenic solution that is used for fluid and electrolyte replenishment. It has metabolic alkalinising ability and is capable of inducing diuresis depending on the clinical condition of the patient.

Dextrose is a monosaccharide that is used as a source of calories and water for hydration. It helps to reduce loss of body protein and nitrogen. It also promotes glycogen deposition in the liver. When used with insulin, it stimulates the uptake of potassium by cells, especially in muscle tissue, thus lowering serum potassium levels.

Dosage & Administration

In case of intermittent peritoneal dialysis (IPD): 2 liters solution is instill into the abdominal cavity over a period of 1 hour then drained from the cavity.

The exchange should be continued for 8-36 hours.

Interaction

There are no known drug interactions and none well documented.

Contraindications

Patients with excessive obesity and in pregnancy.

Side Effects

During dialysis amino acids and water soluble vitamins may be lost. Fluid and electrolyte imbalance, hypovolemia, hypotension or muscle cramping may occur.

Pregnancy & Lactation

Category - Not Classified. FDA has not yet classified the drug into a specified pregnancy category

Precautions & Warnings

It is used for peritoneal dialysis purposes only.

Therapeutic Class

Peritoneal dialysis solution