This solution is indicated when there is combined water and sodium depletion. It provides Dextrose as a nutrient in a suitable medium of Sodium Chloride which is isotonic to body fluid, or it may also be employed as a source of isotonic Sodium Chloride or both. It is usually used in the maintenance and replacement of fluid, electrolyte and carbohydrate in patients who are unable to take fluid and nutrients by mouth e.g. in case of persistent vomiting, during and after surgery, shock or accidents.


This is a sterile solution of Dextrose and Sodium Chloride in water for injection. Each 100 ml of solution contains Dextrose Monohydrate equivalent to Dextrose Anhydrous B.P. 5.0 gm and Sodium Chloride B.P. 0.9 gm. This represents 5% Dextrose in isotonic Sodium Chloride solution. The approximate concentration of sodium and chloride ions in Dextrose is 150 mmol/lit.


Dose is variable. It depends on the clinical condition, age and body surface area of the patients.


  • Check infusion set and infusion solution prior to use.
  • Pull moderately to tear off the protective cover of the Eurocap.
  • Hold lightly the Eurocap but not the bottle body.
  • Open the flow regulator fully and hold the giving set on the top white area, but not the memorane venting region.
  • Insert the spike of the administration set to the Eurocap and fit the connector of the administration set firmly to the needle.
  • Gradually allow the fluid to flow down to the needletip and close.
  • Remove the protective cover of the needle.
  • Locate the venpuncture site and clean the site with an antiseptic solution, and then insert the needle.
  • Securely tape the puncture site.
  • Securely tape the wings and tubing
  • Start infusion while adjusting drip speed.


Do not take this medicine and tell your doctor if: Solutions containing dextrose may be contraindicated in patients with known allergy to corn or corn products.

Side Effects

Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia. If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.

Pregnancy & Lactation

FDA pregnancy category C. It is not known whether dextrose 5% in water will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether dextrose 5% in water passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Precautions & Warnings

As the preparation contains Sodium Chloride, it should be administered with caution to patients with congestive heart failure, peripheral or pulmonary oedema, impaired renal function or pre-eclampsia. Serum glucose concentration should also be carefully monitored and concurrent use of insulin may be needed in case of diabetic patients. Infusion of fluid should be immediately discontinued if rigor arises for any reason during the process. Do not use if the solution is cloudy, contains particles, or after expiry date.

Therapeutic Class

Intravenous fluid preparations, Parenteral nutritional preparations

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Pack Image of Isoride 0.18% 4.3% Injection Pack Image: Isoride 0.18% 4.3% Injection