A-Cold 4 mg/5 ml (Syrup) is a brand of the generic Bromhexine Hyrdochloride. It is manufactured by ACME Laboratories Ltd..

Indications

Bromhexine is indicated in the treatment of respiratory tract disorders associated with productive cough. This include- tracheobronchitis, bronchitis with emphysema, bronchiectasis, bronchitis with bronchospasm, chronic inflammatory pulmonary conditions and pneumoconiosis.

Therapeutic Class

Cough expectorants & mucolytics

Pharmacology

Bromhexine Hydrochloride is an oral mucolytic agent. It disrupts the structure of acid mucopolysaccharide fibres in mucoid sputum and produces less viscous mucus, which makes easier the expectoration. It is rapidly & completely absorbed from the gastrointestinal tract. It is widely distributed into the body tissues.

Dosage & Administration

Adults and Children over 12 years: 10 ml (2 tea-spoonfuls) 3 times daily. May be increased to 20 ml (4 tea-spoonfuls) 3 times daily for the first seven days.

Children 6-11 years: 10 ml (2 tea-spoonfuls) 3 times daily.

Interaction

There are no known significant interactions with other drugs.

Contraindications

It is contraindicated in known hypersensitivity to Bromhexine Hydrochloride or any of the ingredients of this product.

Side Effects

Gastrointestinal side effects may occur occasionally. A transient rise in serum aminotransferase values has been reported. Other reported side effects include-headache, vertigo (dizziness) and allergic reactions.

Pregnancy & Lactation

It is advised not to use it in pregnancy, especially during 1st trimester. Safety during lactation has not been established yet.

Precautions & Warnings

It should be given cautiously to patients with gastric and duodenal ulceration or convulsive disorders. Patients with hepatic and renal insufficiency should take it with caution.

Storage Conditions

Keep in a dry place away from light and heat. Keep out of reach of children.