Bacitracin Zinc + Polymyxin B Sulfate

Indications

This ophthalmic ointment is indicated in the treatment of bacterial infections of the eye and its adnexa including conjunctivitis, keratitis, corneal ulceration and ulcerative blepharitis. It may be applied to prevent ocular infection both pre and post operatively.

Therapeutic Class

Ophthalmic antibacterial drugs

Pharmacology

This ophthalmic ointment is a sterile antimicrobial ointment for ophthalmic use, cointaining Polymixin-B sulphate and Bacitracin Zinc.

Polymixin-B sulphate and Becitracin Zinc are both bactericidal antibiotics, The former exerts its action by binding with the cellular membrane and the later by inhibiting bacterial cell wall development.

Dosage & Administration

Apply the ointment every 3 to 4 hourly for 7 to 10 days, depending on the severity of the infection or as directed by the physician.

Contraindications

Polytracin is contraindicated in those individuals who have shown hypersensitivity to Polymixin-B sulphate, Becitracin Zinc or to cross sensitizing substances.

Side Effects

Sometimes this ointment may be absorbed in the blood, but shows no blood related toxicity. Moreover Allergic reaction, eye irritation, eye redness, itching, swelling may occur.

Pregnancy & Lactation

Bacitracin Zinc: Pregnancy Category C
Polymyxin B Sulphate: Pregnancy Category B
Lactation: Undetermined