Sodium Fusidate (Oral)


Treatment of infections caused by susceptible organisms especially Staph eg, osteomyelitis, septicaemia, endocarditis, superinfected cystic fibrosis, pneumonia, skin & soft tissue infections, surgical & traumatic wound infections.


Fusidic acid inhibits bacterial protein synthesis by interfering with amino acid transfer from aminoacyl-tRNA to protein on the ribosomes.

Dosage & Administration

Adult: 250-500 mg every 8 hourly
Skin & soft tissue infection: 250 mg twice daily.


Drugs metabolized by CYP450 isoenzymes.



Side Effects

GI disturbances eg, dyspepsia, nausea, vomiting, epigastric pain, anorexia; jaundice & change of liver function.

Pregnancy & Lactation

No data found

Precautions & Warnings

Hepatic impairment, biliary obstruction or disease. Monitor hepatic function periodically in patients on high or prolonged oral doses. Avoid during 3rd trimester of pregnancy. Lactation. Premature, jaundiced, acidotic or seriously ill neonates.

Therapeutic Class

Other antibiotic