Calcium + Vitamin D3 + Vitamin C + Vitamin E + Multimineral
Indications
This is indicated for maintaining strong & healthy bones and teeth, prevention & treatment of osteoporosis, postmenopausal osteoporosis, management of glucocorticoid induced osteoporosis.
Composition
Each film coated tablet contains-
- Calcium USP 600 mg,
- Vitamin D3 USP 200 IU,
- Vitamin C BP 60 mg,
- Vitamin E BP 15 IU,
- Magnesium BP 20 mg,
- Zinc BP 7.5 mg,
- Manganese BP 1 mg,
- Boron USP 250 mcg &
- Copper USP 1 mg.
Pharmacology
This medicine is an absolute bone health formula with more than half a dozen key nutrients. Calcium decreases the rate of bone loss from the femoral neck, the spine and the total body. Since calcium is a nutrient, not a drug, the positive effects of supplemental calcium are most pronounced among women with low to moderate calcium intake. Vitamin D3 helps the body to absorb calcium which helps to reduce age-related bone loss and bone fractures related to osteoporosis. Magnesium helps the body to absorb both calcium and vitamin D3. It also helps to synthesize proteins. Low magnesium status has been associated with postmenopausal osteoporosis. The trace minerals Zinc, Copper and Manganese all play a role in bone development. Zinc is a part of an antioxidant enzyme that helps to prevent cellular destruction, which can cause problems with bone growth and maturation. Copper keeps bones free from thinning. Fifty percent of the total copper content in the body is in the bones and muscles. Manganese, in combination with other trace minerals, helps to prevent bone loss and osteoporosis. Boron works with magnesium and vitamin D3 to enhance calcium absorption and helps to maintain calcium levels in the body. Vitamin C works as an antioxidant. It is also essential for the formation of collagen and aids in iron absorption. Vitamin E serves as an antioxidant, protects biological membranes and stabilizes cellular functions.
Dosage & Administration
One tablet twice daily with meals, preferably one tablet in morning & one tablet in evening or as recommended by the doctor. Data regarding use in children & adolescents is insufficient.
Interaction
The risk of hypercalcaemia is increased if calcium salts are given with thiazide diuretics as these drugs reduce urinary calcium excretion. The effects of digitalis glycosides on the heart are enhanced by calcium. Calcium salts may reduce the absorption of fluoride, some fluoroquinolones, tetracyclines and iron.
Contraindications
Patients with known hypersensitivity to any of the tablet ingredients. Absolute contraindications are hyperparathyroidism, renal calculi, malignant bone diseases, sarcoidosis, severe renal failure.
Side Effects
Calcium salts may cause mild gastrointestinal side effects such as constipation, flatulence, nausea, abdominal pain & diarrhea. Hypercalcaemia & in rare cases hypercalciuria have been seen with long term intake of calcium at high doses. Side effects from micronutrients are rare.
Pregnancy & Lactation
Recommended in pregnancy and lactation.
Precautions & Warnings
If there is any pre-existing heart disease or kidney disease, precautions should be taken.
Use in Special Populations
Data is insufficient regarding use in children.
Overdose Effects
Symptoms of overdose may include nausea and vomiting, severe drowsiness, dry mouth, loss of appetite, metalic taste, stomach cramps, unconsciousness, diarrhoea, weakness, headache, constipation, dizziness or irritability.
Therapeutic Class
Specific mineral & vitamin combined preparations
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
