Hydrocortisone Acetate + Benzyl Benzoate + Bismuth Subgallate + Bismuth Oxide + Balsam Peru + Zinc Oxide
Indications
This ointment is indicated for the comprehensive symptomatic treatment of internal and external hemorrhoids and pruritus ani.
Composition
Each 100 gram contains-
- Hydrocortisone Acetate BP 0.25 gm
- Benzyl Benzoate BP 1.25 gm
- Bismuth Subgallate BP 2.25 gm
- Bismuth Oxide Ph.Gr 0.875 gm
- Balsam Peru Ph.Gr 1.875 gm
- Zinc Oxide BP 10.75 gm.
Pharmacology
This ointment provides antiseptic, astringent, emollient and anti-inflammatory actions. Bismuth oxide, zinc oxide, and bismuth subgallate exert a protective action on mucous membranes They are mildly astringent and are reported to have antiseptic properties Balsam Peru has protective properties and a very mild antiseptic action by virtue of its content of cinnamic and benzoic acids. It is believed to promote the growth of epithelial cells, Benzyl benzoate is used as a solubilizing agent and has mild antiseptic and preservative properties. Hydrocortisone acetate has anti-inflammatory action.
Dosage & Administration
Adults (over 18 years): To be applied sparingly to the affected area at night, in the morning and after each evacuation up to a maximum of 4 applications a day. Thoroughly cleanse the affected area, dry and apply ointment on a gauze dressing. For internal conditions use the rectal applicator provided. Use for a maximum period of one week. This is topical administration only.
Pediatric Use: This medicine is not recommended for children under 18 years old.
Pediatric Use: This medicine is not recommended for children under 18 years old.
Interaction
Concurrent use with other corticosteroid preparations either topically or orally may increase the likelihood of systemic effects.
Contraindications
Tubercular, fungal and most viral lesions including herpes simplex vaccinia and varicella, History of sensitivity to any of the constituents.
Side Effects
Prolonged or excessive use may produce systemic corticosteroid effects, and use for periods longer than seven days is not recommended. Rarely, there are sensitivity reactions and Patients may occasionally experience transient burning on application especially if the anoderm is not intact.
Pregnancy & Lactation
There is inadequate evidence of safety in human pregnancy and there may be a very small risk of cleft palate and intrauterine growth retardation as well as suppression of the neonatal hypothalamic-pituitary-adrenal axis. No special precautions required for use during lactation, So Use in pregnancy only when there is no safer alternative and when the disease itself carries risks for the mother or child.
Precautions & Warnings
As with all products containing topical steroids, the possibility of systemic absorption should be borne in mind. Prolonged or excessive use may produce systemic corticosteroid effects, and use for periods longer than seven days is not recommended. The product should be discontinued and the patient advised to consult a medical practitioner if symptoms do not improve or worsen or if rectal bleeding occurs.
Therapeutic Class
Other Topical corticosteroids
Storage Conditions
Do not store above 30°C & keep in a dry place. Protect from light. Do not freeze Keep out of the reach of children.
