Pefloxacin Mesylate Dihydrate
Veterinary
Indications
Poultry: Pefloxacin is indicated for the disease of poultry caused by bacteria and mycoplasma such as Salmonellosis, Colisepticemia, CRD, Infectious Coryza, Pasteurellosis, Mycoplasmosis and for secondary bacterial infection followed by viral infection such as Gumboro and Newcastle diseases.
Fish & Shrimp: Pefloxacin is indicated for the disease of fish & shrimp such as Aromonus, Septicemia, Furunculosis, Columnaria, Vivriosis, Bacterial Gill etc.
Fish & Shrimp: Pefloxacin is indicated for the disease of fish & shrimp such as Aromonus, Septicemia, Furunculosis, Columnaria, Vivriosis, Bacterial Gill etc.
Pharmacology
Bactericidal effect of Pefloxacin is due to its ability to inhibit the activity of bacterial enzymes DNA gyrase which is responsible for the supercoiling of bacterial DNA.
Dosage & Administration
Poultry-
- Prevention: 1 g per 2-4 liter drinking water (2.5-5 mg per kg body weight). Duration: 3-5 days.
- Treatment: 1 g per 1 liter drinking water (10 mg per kg body weight). Duration: 3-5 days.
- 1 g per 20 kg body weight. Duration: 3-5 days.
Interaction
It shows antagonistic reaction if use with chloramphenicol, macrolides or nitrofurans. It's effectiveness may be decreased if use with iron, magnesium, aluminium or zinc.
Contraindications
Contraindicated in animals with known hypersensitivity to Pefloxacin.
Side Effects
It is well tolerated & no side effect has been observed.
Precautions & Warnings
Egg production may be reduced, if used in laying chicken.
Withdrawal period: Meat: 7 days.
Withdrawal period: Meat: 7 days.
Storage Conditions
Store in a cool & dry place, protected from light. Keep all medicines out of the reach of children.