Magaldrate

Indications

Magaldrate is indicated to relieve symptoms of dyspepsia, heartburn, acid indigestion, sour stomach, gastroesophageal reflux, hiatal hernia and flatulence. It is also prescribed in hyperacidity associated with peptic ulcers, gastritis and esophagitis. Magaldrate may be given to children if necessary.

Pharmacology

Magaldrate is a hydroxymagnesium aluminate complex that is converted rapidly in gastric acid to Mg(OH)2 and Al(OH)3, which are absorbed poorly and thus provide a sustained antacid effect

Dosage & Administration

Mild gastric disorders, gastritis: 1-2 tablets / 1-2 teaspoonful, 1-2 hours after meal or at bed time or when required.

Duodenal ulcers, gastric ulcers, reflux oesophagitis: 2-4 tablets / 2-4 teaspoonful, 1-2 hours after meal or at bed time or when required.

Children: Half of the adult dose.

Contraindications

Magaldrate is contraindicated in patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal function

Side Effects

Constipation and diarrhea may occur.

Pregnancy & Lactation

Magaldrate may be used in pregnancy if indicated however one should avoid excessive dosage. Magaldrate may pass into breast milk but has not been reported to cause problem in nursing babies.

Therapeutic Class

Antacids, Anti-dyspeptic/Carminatives