Orofresh OS Oral Solution

This oral solution is indicated in the treatment of acute and chronic inflammations of the mucosas of the mouth, gums and throat (Aphthous Ulcer, Cold Sore, Gingivitis, Periodontitis, Dental Hypersensitivity, Dental Plaque, Denture Irritation).

Each 1 ml oral solution contains Rhubarb extract BP 0.05 gm (equivalent to anthraquinone glycosides 0.005 gm) and Salicylic acid BP 0.01 gm.

This oral solution exerts anti-inflammatory action in the cases of inflammatory infections on the mucosa of the mouth or gums or throat. Its analgesic properties allow to rapidly suppressing pains and the sensitivity of the tissue submitted to inflammatory processes. This oral solution allows that, after a short time, mucosa resume their normal physiological functions, without exerting any harmful action on the tissues. Its use is easy and painless. It is well tolerated by individuals sensitive to iodine.

Salicylic acid works by blocking the action of a substance in the body called cyclo-oxygenase. This extract contains anthraquinone glycosides, which relieve inflammation. This is well absorb into the oral mucosa.

Adults: To be applied to the inflamed oral mucosa (after removing any dentures) 3 to 4 times daily using the brush provided. Avoid rinsing the mouth or eating for 15 minutes after application. Always keep the cap closed immediately after every use.

Children: As per consultation with a registered physician, it is recommended below the age of 12 years.

There are no known interactions with the preparation documented.

Hypersensitivity to any of the constituents.

A transient local burning sensation at the site of application occurs very commonly. Temporary discoloration of teeth or oral mucosa has been described commonly following administration of the oral solution.

Pregnancy: Animal studies are insufficient with respect to effects on pregnancy and-or embryonal/foetal development. The potential risk for humans is unknown. Caution should be exercised when prescribing to pregnant women.

Lactation: Anthraquinone glycosides derived from rhubarb may be excreted in breast milk. However, at therapeutic doses of oral solution, it is not known whether these or salicylic acid are excreted in breast milk. A decision on whether to continue breast feeding or to continue therapy with an oral solution should be made taking into account the benefit of breast-feeding to the child and benefit of oral solution therapy to the woman.

Each bottle of the oral solution should be used by only one person.

Overdose associated with a local application is unlikely, although the extent of systemic absorption of salicylic acid and anthraquinone derivatives is not known. Systemic overdose following ingestion might lead to abdominal cramping, diarrhea, and possibly salicylism (presenting as hyperventilation, tinnitus, deafness, vasodilation, sweating).

Oral preparations

Store in a cool and dry place, protected from light.