60 ml bottle:
৳ 450.00
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Indications
Trugain topical solution is indicated for the treatment of-
- Male androgenetic alopecia (male pattern hair loss) on the top of the scalp (vertex).
- Female androgenetic alopecia (female pattern hair loss) on the top of the scalp.
Pharmacology
Minoxidil topical solution has been shown to stimulate hair growth in males with androgenetic alopecia. The basic change in androgenetic alopecia is the conversion of terminal, non-vellus hair to vellus hair, i.e., hair which is thinner, shorter and less pigmented.
Although the exact mechanism of action of Minoxidil in the treatment of androgenetic alopecia is not known, there may be more than one mechanism by which Minoxidil topical solution stimulates hair growth; they include:
Although the exact mechanism of action of Minoxidil in the treatment of androgenetic alopecia is not known, there may be more than one mechanism by which Minoxidil topical solution stimulates hair growth; they include:
- vasodilation of the micro circulation around the hair follicles which may stimulate hair growth;
- direct stimulation of the hair follicle cells to enter into a proliferative phase;
- resting phase (telogen); follicles being stimulated to pass into growth phase (anagen) follicles.
Dosage & Administration
Minoxidil 2% Solution: A total dose of 1 mL (7 sprays) Minoxidil topical 2% solution (20 mg Minoxidil) should be applied twice per day to the scalp, beginning at the center of the affected area. This dose should be used regardless of the size of the affected area. The total daily dose should not exceed 2 mL (40 mg Minoxidil). Suitable for men and women use.
Minoxidil Topical 5% Solution: Apply 1 mL (7 sprays) 2 times a day directly onto the scalp in the hair loss area. It should be used for men only.
Minoxidil Topical 5% Solution: Apply 1 mL (7 sprays) 2 times a day directly onto the scalp in the hair loss area. It should be used for men only.
Interaction
Trugain topical solution should not be used along with other topical agents known to alter the stratum corneum barrier such as tretinoin or dithranol, due to the enhanced absorption of Trugain. Although there is no clinical evidence, there exists the theoretical possibility of absorbed Trugain potentiating orthostatic hypotension caused by peripheral vasodilators.
Contraindications
- History of sensitivity to Minoxidil
- Treated or untreated hypertension
- Scalp abnormality (including psoriasis and sunburn)
- Shaved scalp
- Occlusive dressings or other topical medical preparations are being used.
Side Effects
- Colds and respiratory infections
- Rhinitis
- Sinusitis
- Coughing
- Scaling
- Itching
- Rash
Pregnancy & Lactation
Systemically absorbed Minoxidil is secreted in human milk. There are no adequate and well controlled studies in pregnant women. Animal studies have shown a risk to the fetus at exposure levels that are very high compared to those intended for human exposure.
Precautions & Warnings
Trugain topical solution is for external use only. Apply only to scalp. Before applying this solution, the user should determine that the scalp is normal and healthy. Hands should be washed thoroughly after use. Inhalation of the spray should be avoided. This solution contains ethanol (alcohol), which will cause burning and irritation of the eye. In the event of accidental contact with sensitive surfaces (eye, abraded skin, mucous membranes), the area should be bathed with large amounts of cool tap water.
Therapeutic Class
Other scalp preparations
Storage Conditions
Do not store above 30°C temperature. Keep away from light and wet place. Keep out of reach of children.
Pack Image: Trugain 2% Scalp Solution