Unit Price:
৳ 3.50
(5 x 10: ৳ 175.00)
Strip Price:
৳ 35.00
Also available as:
Indications
Lansec is indicated for:
- Healing and long term management of gastroesophageal reflux disease.
- Healing and maintenance therapy for patients with duodenal ulcer.
- Relief of reflux-like symptoms (eg. Heartburn) and/or ulcer-like symptoms (eg. upper epigastric pain) associated with acid-related dyspepsia.
- Healing of benign gastric ulcer.
Pharmacology
Lansoprazole is a substituted benzimidazole, and is also known as PPI due to its property to block the final step of acid secretion by inhibiting H+/K+ ATPase enzyme system in gastric parietal cell. Both basal and stimulated acid are inhibited.
Dosage & Administration
Benign gastric ulcer: 30 mg daily in the morning for 8 weeks.
Duodenal ulcer: 30 mg daily in the morning for 4 weeks; maintenance 15 mg.
NSAID-associated duodenal or gastric ulcer: 15-30 mg daily for 4 weeks, followed by a further 4 weeks if not fully healed.
Zollinger-Ellison syndrome (and other hypersecretory conditions): Initially 60 mg once daily adjusted according to response; daily doses of 120 mg or more is given in two divided doses.
Gastroesophageal reflux disease: 30 mg daily in the morning for 4 weeks, followed by a further 4 weeks if not fully healed; maintenance 15-30 mg daily.
Acid-related dyspepsia: 15-30 mg daily in the morning for 2-4 weeks.
Duodenal ulcer: 30 mg daily in the morning for 4 weeks; maintenance 15 mg.
NSAID-associated duodenal or gastric ulcer: 15-30 mg daily for 4 weeks, followed by a further 4 weeks if not fully healed.
Zollinger-Ellison syndrome (and other hypersecretory conditions): Initially 60 mg once daily adjusted according to response; daily doses of 120 mg or more is given in two divided doses.
Gastroesophageal reflux disease: 30 mg daily in the morning for 4 weeks, followed by a further 4 weeks if not fully healed; maintenance 15-30 mg daily.
Acid-related dyspepsia: 15-30 mg daily in the morning for 2-4 weeks.
Interaction
Caution should be exercised when oral contraceptives and preparations such as phenytion, theophylline or warfarin are taken
concomitantly with the administration of Lansec. Antacids and sucralfate may reduce the bioavailability of Lansec.
concomitantly with the administration of Lansec. Antacids and sucralfate may reduce the bioavailability of Lansec.
Contraindications
The use of Lansoprazole is contraindicated in patients with a history of hypersensitivity to any of the ingredients of Lansoprazole capsules.
Side Effects
Lansec is well tolerated, with adverse effects generally being mild and transient. The most commonly reported adverse effects are headache, dizziness, fatigue and malaise. Gastrointestinal effects include diarrhea, constipation, abdominal pain, dyspepsia, nausea, vomiting, flatulence and dry or sore mouths. Dermatological reactions include skin rashes, urticaria and pruritus.
Pregnancy & Lactation
Lansoprazole has been assigned to pregnancy category B by the FDA.
Precautions & Warnings
Symptomatic response to therapy with Lansec does not preclude the presence of gastric malignancy. Lansec should be taken before eating.
Therapeutic Class
Proton Pump Inhibitor
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
