Jasocaine Topical Spray

Jasocaine is a topical anesthetic used for the following purposes-

• To help prevent pain associated with minor surgical procedures in the ear, nose and throat
• To help prevent pain and or discomfort during dental procedures (e.g., prior to an injection)
• During general anesthesia to prevent coughing
• To help prevent pain during the final stages of childbirth, before the cutting or stitching of the perineum (skin between the vagina and anus)

Lidocaine acts mainly by inhibiting sodium influx through sodium specific ion channels in the neuronal cell membrane, in particular the so called voltage-gated sodium channels. When the influx of sodium is interrupted, an action potential cannot arise and signal conduction is inhibited. The receptor site is thought to be located at the cytoplasmic (inner) portion of the sodium channel. Lidocaine binds more readily to sodium channels in activated state, thus onset of neuronal blockade is faster in neurons that are rapidly firing. This is referred to as state dependent blockade.

• Each spray delivers 10 mg of Lidocaine. The maximum dose is 20 sprays (200 mg).
• In dentistry, the normal dose is 1-5 sprays. Two sprays per quarter of the mouth is recommended, with a maximum of 3 sprays per quarter of the mouth over 30 minutes.
• In sinus procedures 3 sprays are used.
• In procedures of the throat and windpipe, up to 20 sprays may be necessary.
• Up to 20 sprays may be necessary in child birth (cesarian procedure).
• Lower doses are used for children aged 3-12 years. Lidocaine 10% Spray is not recommended for children under 3 years.

Should not be given to patients with myasthenia gravis, epilepsy, impaired cardiac condition or liver damage.

Skin rash or irritation, drowsiness, wheezing or difficulty breathing, chest pain, severe rash or itching, increased sweating, numbness.

No study available. Can be given to a pregnant woman as per doctor's judgment. Small amount of Lidocaine may pass to a lactating baby, but the amount is insignificant to cause any harm

Patient should be careful driving or operating machinery after use of Jasocaine 10% Spray. Patient may be drowsy and reflexes may be slow. Patient should not eat or drink anything for at least 1 hour after using Jasocaine 10% Spray in the mouth or throat area. Should be careful not to spray Jasocaine 10% Spray near the eyes. If any of the spray does go in the eye, should rinse immediately with lots of water for at least 15 minutes and doctor should be called.

The first signs that too much Jasocaine 10% Spray has been used usually take the form of light-headedness, drowsiness, dizziness and sometimes blurred vision. In the event of serious over dosage trembling, seizures or unconsciousness may occur.

Local & Surface anesthesia

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.