Prindol Tablet

Prindol is indicated for the treatment of muscle tension/spasm (central and peripheral muscle spasms), neck spasm (torticollis), low back pain (lumbago) and general muscle pain.

Central Muscle Relaxant Effect: Pridinol primarily targets the Central Nervous System (CNS). It acts on the brainstem and the spinal cord, where it selectively inhibits polysynaptic reflexes. In simple terms, when a muscle is injured or strained, the nervous system sends continuous, hyperactive signals causing the muscle to stay locked in a painful contraction (spasm). Pridinol dampens these overactive reflexes, effectively blocking the excessive neurological signals traveling from the spine to the muscles. This allows the skeletal muscles to relax and reduces localized tension.

Anticholinergic (Antimuscarinic) Action: Pridinol possesses distinct antimuscarinic properties. It acts as an antagonist to acetylcholine, a primary neurotransmitter responsible for triggering muscle contractions. By blocking the muscarinic acetylcholine receptors- It directly counters the chemical signals that trigger muscle spasms in both smooth and skeletal muscles. This specific action is also why it helps reduce muscle rigidity and tremors associated with parkinsonism.

The recommended dose is 1.5-3 mg pridinol 3 times daily. The administration is independent of meals, with the onset of the effect being faster when the medicine is taken before a meal. However, if the patient suffers from low blood pressure, take the tablets after meals to reduce the risk of fainting. Or as directed by the registered physician.

Use in Children and Adolescents: No data are available on the use of Pridinol in children and adolescents.

Prindol increases the effect of medicines from the anticholinergic group. Members include, e.g., certain medicines that are used for overactive bladder, urinary incontinence, asthma treatment and in parkinson's disease.

Hypersensitivity to the active substance or to any of the excipients, glaucoma, prostate hypertrophy, syndrome with urinary retention, gastrointestinal obstructions, arrhythmia, first trimester of pregnancy.

Common side effects: Abdominal pain, arrhythmias, asthenia, dizziness, dry mouth, headache, hypotension and nausea.

Rare side effects: Impaired ability to focus, impaired vision, diarrhea, vomiting, hypersensitivity reactions such as itching, redness of the skin, swelling or shortness of breath, impaired attention, coordination, taste, anxiety and depression.

In the first 3 months of pregnancy, Pridinol should not be taken. During the following months of pregnancy, Pridinol may be taken only after careful consideration under medical supervision and only if necessary. There is no data on the passage of Pridinol into human milk. So, using it during breastfeeding should be avoided.

Use with caution in the elderly, patients with liver or kidney problems and hypotension as the risk of circulatory problems (fainting) may be increased. Prindol contains lactose, so, patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption should not take this medicine.

Immediate medical attention is required in case of an overdose.

Centrally acting Skeletal Muscle Relaxants

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.