Powder for Solution

Eraplus Vet Powder for Solution

Veterinary
(25 mg+35 mg+100 mg+18 mg+1.5 mg)/gm
100 gm sachet: ৳ 365.00
10 gm sachet: ৳ 40.00 (10's pack: ৳ 400.00)

Indications

Eraplus Vet is indicated for the prevention & treatment of CRD, CCRD, Bronchopneumonia, Infectious coryza, Colibacillosis, Fowl cholera, Salmonellosis, Diarrhea, Enteritis, Staphylococcal infections etc. in poultry.

Composition

Each gram contains-
  • Erythromycin (as Erythromycin Stearate USP) 25 mg,
  • Neomycin (as Neomycin Sulfate BP) 35 mg,
  • Sulfadimidine (as Sulphadimidine Sodium BP) 100 mg,
  • Trimethoprim BP 18 mg &
  • Bromhexine (as Bromhexine Hydrochloride BP) 1.5 mg.

Pharmacology

Erythromycin is a macrolide antibiotic, which works by binding to the 50S ribosomal subunit of bacteria & Neomycin is an aminoglycoside antibiotic, which irreversibly binds to the 30S ribosomal subunit of bacteria and thereby inhibits bacterial protein synthesis. Sulphadimidine inhibits nucleic acid synthesis by blocking the conversion of Para aminobenzoic Acid (PABA) to co-enzyme dihydrofolic acid & Trymethoprim inhibits the biosynthesis of tetrahydrofolic acid from dihydrofolic acid and thereby inhibits bacterial nucleic acid synthesis. Bromhexine breakdown the structure of Mucopolysaccharide fiber in mucoid sputum & produces less viscous mucus, facilitates the removal of mucus by ciliary action. 

Dosage & Administration

Route of administration- For oral administration only.

Poultry:
  • For prevention- 1 g/Liter drinking water for 4-6 days.
  • For treatment- 2 g/Liter drinking water for 4-6 days.
Or as directed by the registered Veterinary physician.

Interaction

With medicine- Eraplus Vet reduces the absorption of oral penicillin & Vitamin K. Eraplus Vet should not be used with Chloramphenicol, Lincomycin, Clindamycin & azole antifungal drugs.

Contraindications

Contraindicated in poultry hypersensitive to Erythromycin, Neomycin, Sulphadimidine, Trimethoprim & Bromhexine.

Side Effects

Common- Diarrhea, anorexia, vomiting, crystal urea, anemia, thrombocytopenia & leukopenia.
Rare- Allergic reactions, ototoxicity, nephrotoxicity & intestinal malabsorption.

Precautions & Warnings

Use carefully in poultry with impaired liver and kidney functions. Do not use in rabbits, guinea pigs & hamsters. Chronic use of oral aminoglycosides may result in bacterial or fungal superinfections.

Withdrawal Time-
  • Meat- Meat must not be consumed up to 5 days after administration of this medicine.
  • Egg- Egg must not be consumed up to 6 days after administration of this medicine.

Overdose Effects

Well tolerable with recommended dosage regimen. But, acute overdose can result GI distress, CNS toxicity, bone marrow depression & swelling of face.

Storage Conditions

Store below 30ºC temperature and dry place, protected from light. Keep all medicines out of reach of children.
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