Yohimbine is indicated in erectile dysfunction, loss of libido & exhaustion.
The medicinal part of yohimbe is the bark. This evergreen tree grows up to 30 m in height. The bark is gray-brown and the inner fracture is reddish brown and grooved. It tastes bitter and the plant is odorless. The tree grows in the jungles of West Africa, Cameroon, Congo and Gabon. The main alkaloid present in the bark is Yohimbine.
Yohimbe is a potent alpha-2 adrenoceptor blocker and a weak alpha-1 adrenergic antagonist with some antidopaminergic properties. Yohimbe interacts with adrenoceptors that are selectively stimulated by clonidine, alpha-methylnorepinephrine, tramazoline, guanabenz & guanfacin. It also interacts with compounds that are nonselectively stimulated by norepinephrine and epinephrine. Yohimbe has a modest beneficial effect in the management of erectile dysfunction. Because of the alpha-2 adrenergic blockade, the drug is an effective treatment for sexual disorders such as decreased libido and decreased sexual response, caused by selective serotonin reuptake inhibitors.
Dosage & Administration
1 capsule 3 times daily or as advised by the physician
Theoretically, Yohimbe may counteract the hypotensive effect of antihypertensive medications, resulting inadequate blood pressure control. It may potentiate pharmaceutical MAO-inhibitors
The drug should not be used by patients with liver and kidney diseases, chronic inflammation of the sexual organs or prostate gland or with a history of gastric or duodenal ulcers
Anxiety states, elevated blood pressure, exanthema, nausea, insomnia, tachycardia, tremor, mania and vomiting.
Precautions & Warnings
Patients taking Yohimbe should avoid alcohol ingestion
Herbal and Nutraceuticals
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.