Imidocarb

Veterinary

Indications

Imidocarb can be used for prevention & treatment of Babesiosis & Anaplasmosis.

Pharmacology

Imidocarb Dipropionate is an anti-protozoal drug. It exerts its action through two mechanisms i) interference with the production and/or utilization of polyamines, ii) prevention of entry of inositol into the erythrocyte containing the parasite.

Dosage & Administration

For treatment of Babesiosis-
  • Cattle, Sheep: 1 ml/100 kg body weight (In case of mixed infections due to Anaplasma and Babesia, administer 2.5 ml/100 kg body weight. Very severely affected cattle may require a second dose after 24 hours).
  • Horse: 2 ml/100 kg body weight.
  • Dog: 0.25 ml/10 kg body weight.
For treatment of Anaplasmosis-
  • Cattle: 2.5 ml/100 kg body weight.
For Prevention of Babesiosis-
  • Cattle: 2.5 ml/100 kg body weight.
  • Horse: 2 ml/100 kg body weight.
  • Dog: 0.5 ml/10 kg body weight.
The recommended preventive dose of 2.5 ml per 100 kg body weight provides protection against babesiosis for up to four weeks. Or as directed by the Veterinary Physician.

Contraindications

Animals hypersensitive to Imidocarb Dipropionate & having impaired lung, liver & kidney function.

Side Effects

After administration with Imidocarb dipropionate, the animal could come forth some small swelling mass (phyma) as large as a peanut at the injected site and salivate. These symptoms are normal reactions and fade away gradually.

Pregnancy & Lactation

The safety and effectiveness of Imidocarb have not been determined in breeding, lactating or pregnant animals.

Precautions & Warnings

Intravenous administration is totally prohibited.

Toxicity: The sign of acute toxicity is generally consistent with anticholinesterase activity of Imidocarb dipropionate and included lethargy, salivation, lacrimation, ataxia, tremors and convulsions.

Storage Conditions

Keep all medicines out of reach of children. Store in a cool & dry place, protect from light.