Carboxymethylcellulose Sodium

Indications

It is used as a lubricant to relieve irritation and discomfort due to dryness of the eye or due to exposure to wind or sun.

Pharmacology

Carboxymethylcellulose binds to the surface of corneal epithelial cells via its glucopyranose subunits binding to glucose receptors GLUT-1. The residence time of carboxymethylcellulose bound to corneal cells is approximately 2 hours as indicated by a short-term binding assay. Binding of carboxymethylcellulose to the matrix proteins stimulated corneal epithelial cell attachment, migration, and re-epithelialization of corneal wounds.

This eye drop contains Carboxymethylcellulose Sodium similar to normal tears which acts as an ocular lubricant. It provides a lubricating and hydrating protective shield on the ocular surface.

Dosage & Administration

Instill 1 drop in the affected eye(s) 4 times a day or as needed.

Interaction

Not known.

Contraindications

This eye drop is contraindicated in patients with known hypersensitivity to any ingredient of the product.

Side Effects

Burning, Eye Irritation or Pruritus, Visual disturbance, Ocular discharge were reported with this eye drop.

Pregnancy & Lactation

Safe use during pregnancy and lactation has not been established.

Precautions & Warnings

Concomitant ocular medication should be administered 15 minutes prior to the instillation of this eye drop.

Use in Special Populations

Pediatric use: This eye drop should not be used in infants and small children under 3 years.

Geriatric use: No overall differences in safety or effectiveness have been observed between elderly and other adult patients.

Storage Conditions

The drug is to be used within 30 days after the first opening. Store at temperature not exceeding 30°C in a dry place. Protect from light. The bottle is to be closed strongly immediately after use. Keep away from the reach of children.

Available Brand Names