Fenugreek + Gymnema
Indications
Type II diabetes & Hyperlipidemia
Pharmacology
Fenugreek seed is one of the most ancient medicinal herbs. Fenugreek is an annual plant belongs to the family Fabaceae (Leguminosae). The scientific name of Fenugreek is Trigonella foenum-graecum.
The antidiabetic properties of Fenugreek seeds are attributed to the active substances they contain, such as Saponins, Diosgenin, 4-Hydroxyisoleucin, Galactomannan and Trigonelline. These substances demonstrate antidiabetic properties of Fenugreek seeds. Fenugreek seeds contain 50% Saponins, which reduce the rate of glucose absorption in the digestive tract. 4-Hydroxyisoleucin stimulates insulin secretion from the paricreas and also decreases insulin resistance. Galactomannan helps in glucose resorption and Trigonelline improves B-cell regeneration.
Gymnema sylvestre is popularly known as Gurmar for its distinct property as sugar destroyer. The phytoconstituents responsible for sweet suppression activity include Triterpene Saponin known as Gymnemic Acids, Gymnemasaponin and a Polypeptide Gurmarin.
Gymnema sylvestre has good prospects in the treatment of diabetes as it shows positive effects on blood sugar homeostasis, controls sugar cravings and promotes regeneration of pancreas. The herbal extract is used in dietary supplements since it reduces body weight, blood cholesterol and triglyceride levels.
The antidiabetic properties of Fenugreek seeds are attributed to the active substances they contain, such as Saponins, Diosgenin, 4-Hydroxyisoleucin, Galactomannan and Trigonelline. These substances demonstrate antidiabetic properties of Fenugreek seeds. Fenugreek seeds contain 50% Saponins, which reduce the rate of glucose absorption in the digestive tract. 4-Hydroxyisoleucin stimulates insulin secretion from the paricreas and also decreases insulin resistance. Galactomannan helps in glucose resorption and Trigonelline improves B-cell regeneration.
Gymnema sylvestre is popularly known as Gurmar for its distinct property as sugar destroyer. The phytoconstituents responsible for sweet suppression activity include Triterpene Saponin known as Gymnemic Acids, Gymnemasaponin and a Polypeptide Gurmarin.
Gymnema sylvestre has good prospects in the treatment of diabetes as it shows positive effects on blood sugar homeostasis, controls sugar cravings and promotes regeneration of pancreas. The herbal extract is used in dietary supplements since it reduces body weight, blood cholesterol and triglyceride levels.
Dosage & Administration
1 capsule 1-3 times before meals or as directed by a physician.
Interaction
Fenugreek and Gymnema might lower blood sugar levels. Taking Fenugreek and Gymnema along with diabetes medications (Antidiabetic drugs) might cause blood sugar to drop too low. Monitor blood sugar closely. Fenugreek and Gymnema might slow blood clotting. Taking Fenugreek and Gymnema along with Anticoagulant/Antiplatelet drugs/medications that also slow blood clotting might increase the risk of bruising and bleeding. Fenugreek might reduce Theophylline absorption of the body. Using Fenugreek while taking Theophylline might reduce the effects of Theophylline.
Contraindications
Methi Plus is contraindicated in those who are hypersensitive to any component of this product.
Side Effects
The combination of Fenugreek and Gymnema is generally well tolerated. Fenugreek is commonly consumed in foods. It is possibly safe when the powdered seed is taken for up to 3 years. Side effects may include diarrhea, stomach upset, bloating and gas. It may also cause allergic reactions in some people. Gymnema is possibly safe when taken appropriately for up to 20 months.
Pregnancy & Lactation
Sufficient clinical data is not available to use in pregnant women and lactating mother.
Precautions & Warnings
People who are allergic to other plants in the Fabaceae family (including soybeans, peanuts, green peas, and other legumes) might also be allergic to Fenugreek and Gymnema. Fenugreek and Gymnema might slow blood clotting. It might cause extra bleeding during and after surgery. Fenugreek and Gymnema might affect blood sugar levels and could interfere with blood sugar control during and after surgery. Stop taking Fenugreek and Gymnema at least 2 weeks before a scheduled surgery.
Therapeutic Class
Herbal and Nutraceuticals
Storage Conditions
Store in a cool & dry place, Protect from light. Keep out of the reach of the children.
