Oral rehydration salt [glucose based]
Indications
Oral Rehydration Salt helps in replacement of fluid and electrolyte loss due to-
- Acute diarrhea
- Vomiting
- Dehydration
Composition
For 500 ml preparation: Each sachet contains-
- Sodium Chloride BP 1.30 gm
- Potassium Chloride BP 0.75 gm
- Trisodium Citrate Dihydrate BP 1.45 gm
- Glucose Anhydrous BP 6.75 gm
Pharmacology
This is the preparation of oral rehydration salt. It is composed of anhydrous glucose, sodium chloride, potassium chloride and sodium citrate (as dihydrate). This is a single formulation of glucose based oral rehydration salt to treat or prevent dehydration from diarrhea of any etiology, including cholera and in individuals of any age. This also prevents acidosis due to electrolyte imbalance.
Dosage
Daily dose should be equivalent to patients' fluid requirement for maintenance and replenishment of losses. During this therapy, mother should not stop breastfeeding to their child and normal food should be continued in case of adults.
Children less than 2 years: After each loose stool or vomiting 50-100 mL (10 to 20 teaspoonful) of prepared this.
Children 2 to 10 years: After each loose stool or vomiting 100-200 mL (1/2 to 1 glass) of prepared oral saline.
Adult and children above 10 years: After each loose stool or vomiting 200-400 mL (1 to 2 glass) of prepared this.
Children less than 2 years: After each loose stool or vomiting 50-100 mL (10 to 20 teaspoonful) of prepared this.
Children 2 to 10 years: After each loose stool or vomiting 100-200 mL (1/2 to 1 glass) of prepared oral saline.
Adult and children above 10 years: After each loose stool or vomiting 200-400 mL (1 to 2 glass) of prepared this.
Administration
- Disperse the full contents of the sachet in 500 mL (1/2 liter) of pure drinking water.
- Do not mix the oral saline with hot water or heat the prepared solution.
- Discard the unused prepared oral saline after 12 hours of preparation.
Interaction
There are no known drug interactions and none well documented.
Precautions & Warnings
Depressed renal function, severe continuing diarrhea or other critical fluid losses may need supplementation with parenteral fluids along with oral saline.
Therapeutic Class
Oral electrolytes preparations
Storage Conditions
Do not store above 30°C temperature. Keep away from light and wet places. Keep out of reach of children.