Pridinol Mesilate
Indications
Pridinol Mesilate is indicated for the treatment of muscle tension/spasm (central and peripheral muscle spasms), neck spasm (torticollis), low back pain (lumbago) and general muscle pain.
Pharmacology
Pridinol mesilate is a centrally acting muscle relaxant that is used in the symptomatic treatment of muscle spasm. It is also used as the hydrochloride salt for its antimuscarinic activity in the management of parkinsonism.
Dosage & Administration
The recommended dose is 1.5-3 mg pridinol 3 times daily. The administration is independent of meals, with the onset of the effect being faster when the medicine is taken before a meal. However, if the patient suffers from low blood pressure, take the tablets after meals to reduce the risk of fainting. Or as directed by the registered physician.
Use in Children and Adolescents: No data are available on the use of Pridinol in children and adolescents.
Use in Children and Adolescents: No data are available on the use of Pridinol in children and adolescents.
Interaction
Pridinol increases the effect of medicines from the anticholinergic group. Members include, e.g., certain medicines that are used for overactive bladder, urinary incontinence, asthma treatment and in parkinson's disease.
Contraindications
Hypersensitivity to the active substance or to any of the excipients, glaucoma, prostate hypertrophy, syndrome with urinary retention, gastrointestinal obstructions, arrhythmia, first trimester of pregnancy.
Side Effects
Common side effects: Abdominal pain, arrhythmias, asthenia, dizziness, dry mouth, headache, hypotension and nausea.
Rare side effects: Impaired ability to focus, impaired vision, diarrhea, vomiting, hypersensitivity reactions such as itching, redness of the skin, swelling or shortness of breath, impaired attention, coordination, taste, anxiety and depression.
Rare side effects: Impaired ability to focus, impaired vision, diarrhea, vomiting, hypersensitivity reactions such as itching, redness of the skin, swelling or shortness of breath, impaired attention, coordination, taste, anxiety and depression.
Pregnancy & Lactation
Pregnancy: In the first 3 months of pregnancy, Pridinol should not be taken. During the following months of pregnancy, Pridinol may be taken only after careful consideration under medical supervision and only if necessary.
Lactation: There is no data on the passage of Pridinol into human milk. So, using it during breastfeeding should be avoided.
Lactation: There is no data on the passage of Pridinol into human milk. So, using it during breastfeeding should be avoided.
Precautions & Warnings
Use with caution in the elderly, patients with liver or kidney problems and hypotension as the risk of circulatory problems (fainting) may be increased. Pridinol contains lactose, so, patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption should not take this medicine.
Overdose Effects
Immediate medical attention is required in case of an overdose.
Therapeutic Class
Centrally acting Skeletal Muscle Relaxants
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
